Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP16 | P51512 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647331 | 0.84 | PTGS2 (0.47) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL2035096 | 0.80 | CXCL8 (0.46) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL7102472 | 0.78 | PTGS2 (0.47) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL24599305 | 0.77 | GABRA1 (0.46) | PTGS1LMNASMN1; SMN2CYP3A4HPGD | |
| SCHEMBL1261293 | 0.77 | PTGS2 (0.46) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL7381015 | 0.77 | CYP3A4 (0.48) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL2204495 | 0.77 | PTGS2 (0.56) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL15694230 | 0.75 | S1PR1 (0.41) | PTGS1LMNACYP3A4HPGDHIF1A | |
| SCHEMBL7386202 | 0.74 | CXCL8 (0.45) | CXCL8PTGS2MMP2MMP9MMP8 | |
| SCHEMBL3954798 | 0.74 | PTGS2 (0.55) | CXCL8PTGS2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |