Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204495 | 0.84 | PTGS2 (0.56) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL1679256 | 0.84 | CXCL8 (0.44) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL15502398 | 0.82 | CXCL8 (0.47) | PTGS2CXCL8ALDH1A1 | |
| SCHEMBL20921259 | 0.79 | KMT2A (0.44) | PTGS2PTGS1MAPTHPGDMEN1 | |
| SCHEMBL4160190 | 0.79 | KMT2A (0.44) | PTGS2PTGS1MAPTHPGDMEN1 | |
| SCHEMBL1343676 | 0.78 | PTGS2 (0.50) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL18797642 | 0.78 | PTGS2 (0.50) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL1667434 | 0.77 | CYP2D6 (0.41) | PTGS2PTGS1KMT2ALMNAHIF1A | |
| SCHEMBL153695 | 0.77 | PTGS2 (0.59) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL38662145 | 0.77 | LMNA (0.52) | PTGS2HPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| WO-2026097145-A1 | FAK INHIBITORS | AMPLIA THERAPEUTICS LIMITED (AU) | 2026-05-15 | — | — | WO | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109642908-B | Compounds useful for treating metabolic disorders | 哈佛学院院长及董事 | 2022-08-16 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113121450-A | Alpha-amino-beta-carboxymuconate semialdehyde decarboxylase inhibitors | TES制药有限责任公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-112218913-A | Porous body and method for producing porous body | 株式会社伊玛尔斯京都 | 2021-01-12 | — | — | CN | disclosed |
| CN-107207483-B | Alpha-amino-beta-carboxymuconate semialdehyde decarboxylase inhibitors | TES制药有限责任公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-104736533-B | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2016-12-07 | — | — | CN | disclosed |
| US-20160030568-A1 | COMPOSITIONS CAPABLE OF FACILITATING PENETRATION ACROSS A BIOLOGICAL BARRIER | CHIASMA INC. (US) | 2016-02-04 | — | — | US | disclosed |
| EP-0944394-A4 | TREATMENT OF HIV-INFECTION BY INTERFERING WITH HOST CELL CYCLOPHILIN RECEPTOR ACTIVITY | PICOWER INST MED RES (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0944394-A1 | TREATMENT OF HIV-INFECTION BY INTERFERING WITH HOST CELL CYCLOPHILIN RECEPTOR ACTIVITY | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5856322-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1999-01-05 | — | — | US | disclosed |
| EP-0480717-B1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997033604-A1 | TREATMENT OF HIV-INFECTION BY INTERFERING WITH HOST CELL CYCLOPHILIN RECEPTOR ACTIVITY | PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5565473-A | USEFUL AS ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE AGENTS; MONTELUKAST AND ITS SODIUM SALT | MERCK FROSST CANADA, INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| WO-1994012663-A9 | IDENTIFICATION AND PURIFICATION OF SERINE ESTERASE ENZYMES | — | 1994-07-21 | — | — | WO | disclosed |
| WO-1994012663-A1 | IDENTIFICATION AND PURIFICATION OF SERINE ESTERASE ENZYMES | MEDICAL RESEARCH COUNCIL (GB) | 1994-06-09 | — | — | WO | disclosed |
| US-5270324-A | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-12-14 | — | — | US | disclosed |
| EP-0480717-A1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |