Benzophenone

Benzophenone

SCHEMBL1679294

CC(C)(C)OC(=O)[C@@H](N)Cc1ccccc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.56
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
LTA4H P09960 2/20 0.46
ITGA4 P13612 1/20 0.45
ITGB7 P26010 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
PPARD Q03181 2/20 0.44
SLC15A1 P46059 1/20 0.44
ATM Q13315 1/20 0.43
AAK1 Q2M2I8 1/20 0.43
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MMP1 P03956 1/20 0.42
MMP3 P08254 1/20 0.42
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL1679572 1.00 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL314142 0.93 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL594132 0.93 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1221379 0.93 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL237073 0.91 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL594131 0.91 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL18321716 0.91 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL237074 0.91 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Acetic Acid SCHEMBL7710564 0.91 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3528768 0.83 SLC7A5 (0.68) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1712549-B1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO LTD (JP) 2018-04-11 EP disclosed
US-8716524-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2014-05-06 US disclosed
US-8697910-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2014-04-15 US disclosed
US-20110152562-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO., LTD. (JP) 2011-06-23 US disclosed
US-7928224-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2011-04-19 US disclosed
US-20070161624-A1 Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same KISHIDA CHEMICAL CO., LTD. (JP) 2007-07-12 US disclosed
US-20070135654-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO., LTD (JP) 2007-06-14 US disclosed
EP-1712549-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & COMPANY, LTD. (JP) 2006-10-18 EP disclosed
EP-1277755-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT WITH AXIAL ASYMMETRY, PROCESS FOR PRODUCING THE SAME, AND APPLICATION TO ASYMMETRIC SYNTHESIS OF $g(a)-AMINO ACID DERIVATIVE Nagase & Co., Ltd. (JP) 2003-01-22 EP disclosed
US-6441231-B1 SPIRO QUARTERNARY AMMONIUM SALT COMPOUNDS, USED AS PHASE TRANSFER CATALYST FOR STEREOSELECTIVE ALKYLATION NAGASE & CO., LTD. (JP) 2002-08-27 US disclosed
US-20020103374-A1 OPTICALLY ACTIVE QUARTERNARY AMMONIUM SALT WITH AXIAL CHIRALITY, METHOD FOR PRODUCING THEREOF, AND APPLICATION THEREOF FOR ASYMMETRIC SYNTHESIS OF ALPHA-AMINO ACID NAGASE & CO., LTD (JP) 2002-08-01 US disclosed
US-20020065414-A1 Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and aplication thereof for asymmetric synthesis of alpha-amino acid NAGASE & CO., LTD. (JP) 2002-05-30 US disclosed
US-6340753-B1 CATIONIC QUATERNARY AMMONIUM COMPOUNDS DEHYDROHALOGENATION OF COMPOUNDS TO FORM AMINES NAGASE & CO., LTD. (JP) 2002-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135654-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME BCAT1, BCAT2, AADAT SLC7A5 11/4885ALPI 959/4885PKM 3248/4885
US-20020065414-A1 Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and aplication thereof for asymmetric synthesis of alpha-amino acid AADAT, AASDHPPT, BCAT1 SLC7A5 47/4885ALPI 1423/4885PKM 2588/4885
US-20020103374-A1 OPTICALLY ACTIVE QUARTERNARY AMMONIUM SALT WITH AXIAL CHIRALITY, METHOD FOR PRODUCING THEREOF, AND APPLICATION THEREOF FOR ASYMMETRIC SYNTHESIS OF ALPHA-AMINO ACID AADAT, BCAT1, BCAT2 SLC7A5 27/4885ALPI 1327/4885PKM 3016/4885
US-20110152562-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME BCAT1, AADAT, BCAT2 SLC7A5 10/4885ALPI 968/4885PKM 3657/4885
US-20070161624-A1 Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same BCAT1, BCAT2, AADAT SLC7A5 11/4885ALPI 959/4885PKM 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.