Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795006 | 0.86 | CSF1R (0.41) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16794922 | 0.77 | MMP2 (0.36) | HPGDCYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL16794835 | 0.74 | CSF1R (0.50) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16795061 | 0.74 | PADI4 (0.45) | CSF1RNPSR1MEN1KMT2AHSD17B10 | |
| SCHEMBL16794921 | 0.70 | LMNA (0.37) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16794929 | 0.70 | CNR2 (0.39) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16814454 | 0.70 | CSF1R (0.63) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16794939 | 0.67 | CSF1R (0.47) | CSF1RHPGDCYP1A2CYP2C19MEN1 | |
| SCHEMBL16814655 | 0.67 | ALDH1A1 (0.44) | CSF1RHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL16794889 | 0.66 | NTRK1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |