Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.56 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590338 | 0.82 | SIGMAR1 (0.73) | SIGMAR1SLC6A12TEAD1MEN1KMT2A | |
| SCHEMBL16795141 | 0.81 | CXCR3 (0.51) | SIGMAR1SLC6A12TEAD1MEN1KMT2A | |
| SCHEMBL17557652 | 0.80 | SIGMAR1 (0.75) | SIGMAR1KMT2A | |
| SCHEMBL2425554 | 0.79 | SIGMAR1 (0.78) | SIGMAR1SLC6A12KMT2A | |
| SCHEMBL1606020 | 0.78 | SIGMAR1 (0.68) | SIGMAR1SLC6A12KMT2A | |
| Hydrochloric Acid SCHEMBL21410212 | 0.77 | SIGMAR1 (0.76) | SIGMAR1SLC6A12KMT2A | |
| SCHEMBL16795119 | 0.77 | L3MBTL1 (0.46) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6312739 | 0.77 | SIGMAR1 (0.76) | SIGMAR1SLC6A12MEN1KMT2A | |
| SCHEMBL20640315 | 0.76 | SIGMAR1 (0.73) | SIGMAR1TEAD1KMT2A | |
| SCHEMBL20570029 | 0.76 | ATM (0.47) | SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |