Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795223 | 0.81 | SIGMAR1 (0.56) | SIGMAR1MEN1KMT2ATEAD1SLC6A12 | |
| SCHEMBL16795119 | 0.80 | L3MBTL1 (0.46) | SIGMAR1MEN1KMT2AACHEBACE1 | |
| SCHEMBL16795145 | 0.79 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL16795229 | 0.74 | CXCR3 (0.36) | CXCR3SIGMAR1ACHEBACE1BCHE | |
| SCHEMBL8408423 | 0.74 | ACHE (0.66) | CXCR3SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL7424698 | 0.73 | ACHE (0.64) | CXCR3SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL8805002 | 0.73 | ACHE (0.64) | CXCR3SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL13202834 | 0.73 | L3MBTL1 (0.53) | CXCR3SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL16795154 | 0.73 | POLB (0.56) | MEN1KMT2A | |
| SCHEMBL14981031 | 0.71 | L3MBTL1 (0.58) | SIGMAR1MEN1KMT2AACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |