Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076994 | 0.83 | ALDH1A1 (0.40) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL996835 | 0.80 | CYP1A2 (0.44) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL10983387 | 0.80 | GABRP (0.46) | KDM4EGAAHSD17B10SMN1; SMN2GABRP | |
| SCHEMBL7676286 | 0.79 | KDM4E (0.44) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL27615088 | 0.78 | ALDH1A1 (0.41) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL788899 | 0.78 | SELL (0.45) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL18929968 | 0.77 | ALDH1A1 (0.50) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7160625 | 0.77 | KDM4E (0.41) | KDM4EGAAHSD17B10GABRPGABRD | |
| SCHEMBL5412420 | 0.76 | MEN1 (0.34) | KDM4EGAANPSR1ALDH1A1KMT2A | |
| SCHEMBL6526829 | 0.75 | SELL (0.52) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087343-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF NILOTINIB AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2015-06-18 | — | — | WO | claimed |
| WO-2015087343-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF NILOTINIB AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2015-06-18 | — | — | WO | disclosed |