Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | HAAO | P46952 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788899 | 0.90 | SELL (0.45) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL2925754 | 0.83 | SELL (0.52) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL9867697 | 0.83 | CA12 (0.39) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL299374 | 0.81 | SELL (0.41) | KDM4EHSD17B10GAATSHRSMN1; SMN2 | |
| SCHEMBL2374014 | 0.80 | HPGD (0.42) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL7412901 | 0.80 | MMP2 (0.44) | KDM4EHSD17B10ALDH1A1GAATSHR | |
| SCHEMBL10741043 | 0.80 | ERN1 (0.42) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL8316943 | 0.80 | GABRA1 (0.39) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL6526829 | 0.79 | SELL (0.52) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL2581660 | 0.79 | KDM4E (0.50) | KDM4EHSD17B10HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920413-B1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX INC (US) | 2002-11-13 | — | — | EP | claimed |
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0231139-A2 | Dihydrobenzofurane and chromane carboxamide derivatives, processes for their preparation and their use as neuroleptics | Laboratoires DELAGRANGE (FR) | 1987-08-05 | — | — | EP | disclosed |