Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615088 | 0.88 | ALDH1A1 (0.41) | ALDH1A1CASP6CDC25BRCE1KDM4E | |
| SCHEMBL16795486 | 0.83 | KDM4E (0.42) | ALDH1A1CASP6KDM4EKMT2AMAPT | |
| SCHEMBL996835 | 0.83 | CYP1A2 (0.44) | ALDH1A1KDM4EKMT2AHSD17B10TSHR | |
| SCHEMBL27677857 | 0.83 | MAPT (0.47) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL7412901 | 0.81 | MMP2 (0.44) | ALDH1A1CASP6CDC25BRCE1KDM4E | |
| SCHEMBL461024 | 0.79 | MMP2 (0.50) | ALDH1A1CASP6CDC25BRCE1KDM4E | |
| SCHEMBL11501049 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CDC25BKDM4EKMT2AMAPT | |
| SCHEMBL788899 | 0.77 | SELL (0.45) | ALDH1A1KDM4EKMT2ARXFP1MAPT | |
| SCHEMBL2927788 | 0.77 | GABRP (0.47) | ALDH1A1CASP6CDC25BRCE1KDM4E | |
| SCHEMBL10706688 | 0.77 | TSHR (0.40) | ALDH1A1CASP6CDC25BRCE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572560-B1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2021202876-A1 | POLYURETHANE PREPOLYMER COMPOSITION COMPRISING AN ALKYL BENZOATE | LANXESS CORPORATION (US) | 2021-10-07 | — | — | WO | disclosed |
| EP-0677542-B1 | Diamine chain extenders in polyurethane-ureas and process of manufacture | AIR PROD & CHEM (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5719307-A | INCLUDING 2-METHYL-1,3-PROPANEDIOL-BIS-PARA-AMINOBENZOATE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0677542-A2 | Diamine chain extenders in polyurethane-ureas and process of manufacture | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5371288-A | Branched alkyl-containing aminobenzamides as chain extenders in polyurethane-urea elastomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-4365051-A | CURING AGENTS, CHAIN EXTENSION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| US-4254272-A | PHENYL OR CYCLOHEXYL ESTER OF 3,5-DIAMINO-4-TERT-BUTYL-BENZOIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4222955-A | CURING AGENT FOR POLYURETHANES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-09-16 | — | — | US | disclosed |
| US-4187186-A | WEAR, OXIDATION AND CORROSION RESISTANT | MOBIL OIL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |