Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158216 | 0.87 | AKR1C3 (0.59) | AKR1C3CDC25BATMPOLBNR4A1 | |
| SCHEMBL19244787 | 0.85 | CES2 (0.50) | AKR1C3MYCATMALBGAA | |
| SCHEMBL1420986 | 0.84 | ALDH1A1 (0.59) | AKR1C3ATMGAACES2CES1 | |
| SCHEMBL144047 | 0.82 | AKR1C3 (0.76) | AKR1C3MYCCDC25BATMPOLB | |
| SCHEMBL30978151 | 0.82 | AKR1C3 (0.76) | AKR1C3MYCCDC25BATMPOLB | |
| SCHEMBL333008 | 0.82 | AKR1C3 (0.61) | AKR1C3CDC25BATMGAAMAPT | |
| SCHEMBL29433447 | 0.82 | AKR1C3 (0.61) | AKR1C3CDC25BATMGAAMAPT | |
| SCHEMBL29592539 | 0.82 | ALB (0.63) | AKR1C3CDC25BNR4A1ALBCES2 | |
| SCHEMBL335939 | 0.82 | ALB (0.63) | AKR1C3CDC25BNR4A1ALBCES2 | |
| SCHEMBL857849 | 0.82 | AKR1C3 (0.67) | AKR1C3MYCCDC25BATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942456-A | Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors | SOSEI R & D LTD (GB) | 2007-04-04 | — | — | CN | disclosed |
| EP-1740558-A1 | BENZOXAZOCINES AND THEIR THERAPEUTIC USE AS MONOAMINE REUPTAKE INHIBITORS | Sosei R&D Ltd. (GB) | 2007-01-10 | — | — | EP | disclosed |
| US-20060019940-A1 | Novel benzoxazocines and their therapeutic use | SOSEI R&D LTD. (GB) | 2006-01-26 | — | — | US | disclosed |
| WO-2005103019-A1 | BENZOXAZOCINES AND THEIR THERAPEUTIC USE AS MONOAMINE REUPTAKE INHIBITORS | SOSEI R&D LTD. (GB) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019940-A1 | Novel benzoxazocines and their therapeutic use | HTR4, OPRM1, GRM4 | AKR1C3 3345/4885MYC 4798/4885CDC25B 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.