Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300998 | 0.90 | NPC1 (0.57) | NPC1RAB9AMMP2MMP9MMP12 | |
| SCHEMBL16796021 | 0.84 | NPC1 (0.53) | NPC1RAB9AMMP2MMP9MMP12 | |
| SCHEMBL1746493 | 0.80 | MMP2 (0.55) | MMP2MMP9MMP12HPGDSMN1; SMN2 | |
| SCHEMBL29855934 | 0.78 | NPC1 (0.66) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL4444737 | 0.78 | NPC1 (0.66) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL16796015 | 0.77 | CA12 (0.51) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL4308501 | 0.77 | NPC1 (0.44) | NPC1RAB9AMMP2MMP9MMP12 | |
| SCHEMBL4301156 | 0.76 | L3MBTL1 (0.53) | MMP2MMP9MMP12HPGDSMN1; SMN2 | |
| Benzene SCHEMBL28318261 | 0.76 | AKR1C3 (0.61) | NPC1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL6545581 | 0.75 | HNF4A (0.49) | NPC1MMP2MMP9MMP12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303733-B1 | FROM BISPHENOL COMPOUNDS AND DIFLUORO DIARYLACETYLENES AND/OR ETHYNYLATED BENZOPHENONES; DIELECTRICS EMPLOYED WITH A VARIETY OF MICROELECTRONIC DEVICES, FOR EXAMPLE, INTEGRATED CIRCUITS AND MULTICHIP MODULES. | ALLIEDSIGNAL INC. | 2001-10-16 | — | — | US | claimed |
| WO-2000031163-A2 | POLY(ARYLENE ETHER) HOMOPOLYMER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 2000-06-02 | — | — | WO | claimed |