Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927314 | 0.84 | TSHR (0.38) | TSHRACHEALDH1A1TDP1NPC1 | |
| SCHEMBL19926964 | 0.79 | TSHR (0.33) | TSHRACHETDP1ESR1 | |
| SCHEMBL19926864 | 0.79 | TSHR (0.33) | TSHRACHETDP1 | |
| SCHEMBL7935157 | 0.76 | TSHR (0.43) | TSHRACHEALDH1A1TDP1NPC1 | |
| SCHEMBL43315 | 0.74 | TSHR (0.41) | TSHRACHEALDH1A1TDP1NPC1 | |
| SCHEMBL1679852 | 0.74 | TSHR (0.41) | TSHRACHEALDH1A1TDP1NPC1 | |
| SCHEMBL2183250 | 0.72 | TSHR (0.35) | TSHRACHEALDH1A1NPC1RAB9A | |
| SCHEMBL21112789 | 0.71 | ACHE (0.38) | TSHRACHEALDH1A1TDP1ESR1 | |
| SCHEMBL704261 | 0.71 | ACHE (0.38) | TSHRACHEALDH1A1TDP1ESR1 | |
| SCHEMBL706201 | 0.71 | ACHE (0.38) | TSHRACHEALDH1A1TDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611203-B1 | CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION FOR OPTICAL TRANSMISSION COMPONENTS, OPTICAL TRANSMISSION COMPONENTS, AND FABRICATION PROCESS THEREOF | DOW CORNING (US) | 2011-04-06 | — | — | EP | disclosed |
| US-20070025678-A1 | Curable organopolysiloxane resin composition for optical transmission components, optical transmission components, and fabrication process thereof | DOW CORNING CORPORATION | 2007-02-01 | — | — | US | disclosed |
| EP-1611203-A2 | CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION FOR OPTICAL TRANSMISSION COMPONENTS, OPTICAL TRANSMISSION COMPONENTS, AND FABRICATION PROCESS THEREOF | DOW CORNING ASIA Ltd (JP) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004090041-A2 | CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION FOR OPTICAL TRANSMISSION COMPONENTS, OPTICAL TRANSMISSION COMPONENTS, AND FABRICATION PROCESS THEREOF | DOW CORNING ASIA LTD. (JP) | 2004-10-21 | — | — | WO | disclosed |
| EP-0163495-B1 | LIQUID CRYSTALLINE ORGANOSILICON COMPOUNDS | Toray Silicone Company Limited (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4774028-A | Liquid crystalline organosilicon compounds | TORAY SILICONE CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0163495-A2 | Liquid crystalline organosilicon compounds | Toray Silicone Company Limited (JP) | 1985-12-04 | — | — | EP | disclosed |