SCHEMBL704261

SCHEMBL704261

Cc1ccccc1[SiH2]OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.38
TSHR P16473 1/20 0.38
ESR1 P03372 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CYP3A4 P08684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961141 0.86 MAPK1 (0.33) TSHRALDH1A1TDP1
SCHEMBL705275 0.83 TRPA1 (0.40) TSHRALDH1A1CA1CA2CA7
SCHEMBL28872550 0.77 ALDH1A1 (0.34) ALDH1A1CA1CA2
SCHEMBL704634 0.77 TDP1 (0.40) TSHRALDH1A1CA2TDP1
SCHEMBL7935157 0.75 TSHR (0.43) ACHETSHRESR1ALDH1A1CA1
SCHEMBL705571 0.74 GABRA1 (0.39) TSHRALDH1A1CA1CA2CYP3A4
SCHEMBL706208 0.74 GABRA1 (0.39) TSHRALDH1A1
SCHEMBL16487295 0.74 ALDH1A1 (0.39) ACHETSHRALDH1A1CA1CA2
SCHEMBL6751438 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1679852 0.73 TSHR (0.41) ACHETSHRESR1ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed