SCHEMBL43315

SCHEMBL43315

Cc1ccccc1[SiH2]O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ACHE P22303 2/20 0.41
ALDH1A1 P00352 3/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
CYP2A6 P11509 2/20 0.31
CYP1A2 P05177 2/20 0.31
MGLL Q99685 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2213216 0.83 TSHR (0.35) TSHRACHE
SCHEMBL1894227 0.82 TRPA1 (0.38) TSHRACHEALDH1A1CA1CA2
SCHEMBL15621999 0.79 CYP1A2 (0.31) ALDH1A1CA1CA2CA7CA9
SCHEMBL15551737 0.79 ALDH1A1 (0.33) ALDH1A1CA1CA2CA7CA9
SCHEMBL7935157 0.78 TSHR (0.43) TSHRACHEALDH1A1CA1CA2
SCHEMBL1679852 0.76 TSHR (0.41) TSHRACHEALDH1A1CA1CA2
SCHEMBL1679710 0.74 TSHR (0.39) TSHRACHEALDH1A1CA1CA2
SCHEMBL2146499 0.73 CA1 (0.50) TSHRALDH1A1CA1CA2CA7
SCHEMBL704261 0.73 ACHE (0.38) TSHRACHEALDH1A1CA1CA2
SCHEMBL21112789 0.73 ACHE (0.38) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5862 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107203-A1 WEARABLE NON-INVASIVE ELECTROENCEPHALOGRAM AND ULTRASOUND DEVICE FOR DEEP BRAIN STIMULATION IN RAPID EYE MOVEMENT SLEEP ENHANCEMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-21 WO claimed
CN-120649193-B Organic silicon fiber and preparation method thereof 苏州大学 2026-05-12 CN claimed
CN-122011331-A Preparation method of high-hydrophobicity corrosion-resistant fluorine-containing polyurea material 沈阳化工大学 2026-05-12 CN claimed
WO-2025262549-A1 3-DIMENSIONAL VASCULAR MODELS ETH Zürich (CH) 2025-12-26 WO claimed
EP-4668249-A1 3-DIMENSIONAL VASCULAR MODELS ETH Zurich (CH) 2025-12-24 EP claimed
CN-119977357-A Syringe of prefilled hydrogen peroxide solution having excellent hydrogen peroxide storage property due to oil composition containing silicone oil 日本合同会社KORTUC 2025-05-13 CN claimed
US-20250110416-A1 METHODS OF PREPARING AN ORGANIC PHOTOCONDUCTOR DRUM HAVING AN OVERCOAT TO MITIGATE CLEANER BLADE FLIP BANK TRUST COMPANY, NATIONAL ASSOCIATION 2025-04-03 US claimed
US-20250110415-A1 ORGANIC PHOTOCONDUCTOR DRUM HAVING AN OVERCOAT TO MITIGATE CLEANER BLADE FLIP BANK TRUST COMPANY, NATIONAL ASSOCIATION 2025-04-03 US claimed
CN-116333240-B Boron siloxane modified phenolic resin flame retardant, transparent flame-retardant polycarbonate composite material and preparation method thereof 上海锦湖日丽塑料有限公司 2025-03-25 CN claimed
CN-119679646-A Use of active substances and compositions thereof 上海克琴科技有限公司 2025-03-25 CN claimed
US-4331622-A Method for manufacturing a microporous film having low electrical resistance and high durability ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-05-25 US claimed
EP-0037266-A2 Method and apparatus for controlling the temperature of or indicating the presence of a material by means of a waveguide, heat activatable articles incorporating waveguides; and novel waveguides and a method of making such waveguides RAYCHEM CORPORATION (a California corporation) (US) 1981-10-07 EP claimed
US-4292253-A Organo-metal catalysts and processes for their preparation OZIN GEOFFREY A 1981-09-29 US claimed
US-4210709-A POLYOLEFIN MATRIX WITH INORGANIC FILLER AND ACID-RESISTANT ORGANIC SUBSTANCE ADHERING TO SURFACE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-01 US claimed
US-4150013-A Melt processible tetrafluoroethylene copolymers containing organo polysiloxanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-17 US claimed
US-4053581-A ANTIPERSPIRANT SOLUTION CONTAINING A MIXTURE OF SUBSTANTIALLY VOLATILE AND SUBSTANTIALLY NON-VOLATILE SILOXANE LIQUIDS LEVER BROTHERS COMPANY (US) 1977-10-11 US claimed
US-4031059-A SILOXANE ELASTOMER RESINS MARTIN MARIETTA CORPORATION (US) 1977-06-21 US claimed
US-4016328-A SILICONE RESIN, SILICONE GUM, 2,4-DICHLOROBENZOYL PEROXIDE AS CURING AGENT GENERAL ELECTRIC COMPANY (US) 1977-04-05 US claimed
US-4014710-A IRON OXIDE, MAGNETIC TAPES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US claimed
US-3947184-A IMAGING METHOD XEROX CORPORATION (US) 1976-03-30 US claimed