SCHEMBL16797634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3485036	0.84	KMT2A (0.56)	KMT2ASMN1; SMN2L3MBTL1LMNAMAOB
	SCHEMBL2381049	0.82	KMT2A (0.60)	KMT2ASMN1; SMN2MAOBALOX5NR4A2
	SCHEMBL6366231	0.81	L3MBTL1 (0.52)	L3MBTL1TSHRMAPK1TDP1
	SCHEMBL6366230	0.81	L3MBTL1 (0.52)	L3MBTL1TSHRMAPK1TDP1
	SCHEMBL15232861	0.81	KMT2A (0.59)	KMT2ASMN1; SMN2MAOBALOX5NR4A2
	SCHEMBL5379536	0.81	KMT2A (0.53)	KMT2ASMN1; SMN2L3MBTL1LMNAMAOB
	SCHEMBL4951331	0.81	KMT2A (0.53)	KMT2ASMN1; SMN2L3MBTL1LMNAMAOB
	SCHEMBL6366936	0.80	HPGD (0.55)	KMT2ASMN1; SMN2MEN1
	SCHEMBL5811954	0.79	MMP8 (0.54)	KMT2ALMNAMEN1
	SCHEMBL10635430	0.79	MMP8 (0.54)	KMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.