SCHEMBL16797645

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16809563	0.87	KCNH2 (0.53)	SIGMAR1KCNH2GRIN2BMIFALDH1A1
	SCHEMBL16809670	0.87	SIGMAR1 (0.52)	SIGMAR1KCNH2GRIN2BMIFALDH1A1
	SCHEMBL16809424	0.86	KCNH2 (0.55)	SIGMAR1KCNH2GRIN2BMIFALDH1A1
	SCHEMBL16809696	0.81	SIGMAR1 (0.49)	SIGMAR1KCNH2GRIN2BMIFL3MBTL1
	SCHEMBL9692745	0.80	SIGMAR1 (0.42)	SIGMAR1KCNH2GRIN2BALDH1A1MAPT
	SCHEMBL18169340	0.78	PPARG (0.36)	SIGMAR1KCNH2GRIN2BALDH1A1MAPT
	SCHEMBL16809472	0.77	SIGMAR1 (0.41)	SIGMAR1POLBKDM4E
	SCHEMBL16797662	0.76	SIGMAR1 (0.47)	SIGMAR1KCNH2GRIN2BALDH1A1MAPT
	SCHEMBL16809545	0.75	SIGMAR1 (0.43)	SIGMAR1
	SCHEMBL19905634	0.74	SIGMAR1 (0.48)	SIGMAR1KCNH2GRIN2BMIFALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.