Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692444 | 0.83 | HIF1A (0.39) | SIGMAR1ALDH1A1MAPTGAAPOLB | |
| SCHEMBL16797645 | 0.80 | SIGMAR1 (0.53) | SIGMAR1KCNH2GRIN2BALDH1A1MAPT | |
| SCHEMBL16809670 | 0.77 | SIGMAR1 (0.52) | SIGMAR1KCNH2GRIN2BALDH1A1MAPT | |
| SCHEMBL9692382 | 0.76 | SMN1; SMN2 (0.37) | POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL9691985 | 0.75 | LTA4H (0.37) | POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL16809563 | 0.75 | KCNH2 (0.53) | SIGMAR1KCNH2GRIN2BALDH1A1MAPT | |
| SCHEMBL16809424 | 0.74 | KCNH2 (0.55) | SIGMAR1KCNH2GRIN2BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9692609 | 0.74 | LTA4H (0.37) | POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL9690440 | 0.74 | SMN1; SMN2 (0.34) | POLBKDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL9691921 | 0.72 | HTT (0.35) | KCNH2ALDH1A1POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112855-A | Nootropic Agents | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4957928-A | NOOTROPIC AGENTS, COGNITION ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |