Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679897 | 0.80 | CSF1R (0.36) | CSF1RKMT2AEGLN2CDK8ACVR1 | |
| SCHEMBL469902 | 0.70 | CRHR1 (0.34) | MAPTTP53CDK8ACVR1POLB | |
| SCHEMBL513464 | 0.69 | ESRRA (0.36) | MAPTKMT2ATP53MEN1CDK8 | |
| SCHEMBL12906309 | 0.69 | CDK8 (0.42) | TP53CDK8ACVR1KDM4EALDH1A1 | |
| SCHEMBL513319 | 0.69 | NMT1 (0.36) | KMT2ACDK8ACVR1ALDH1A1 | |
| SCHEMBL20695057 | 0.68 | POLB (0.33) | MAPTKMT2AMEN1CDK8ACVR1 | |
| SCHEMBL513475 | 0.65 | NMT1 (0.33) | MAPTCDK8ACVR1KDM4EALDH1A1 | |
| SCHEMBL18797100 | 0.65 | CYP3A4 (0.34) | MAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL22500189 | 0.65 | MAPT (0.38) | MAPTKMT2ATP53MEN1CDK8 | |
| SCHEMBL22499974 | 0.65 | MAPK8 (0.39) | CSF1RMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045271-A1 | HERBICIDALLY ACTIVE, HETEROCYCLYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |