Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797089 | 0.84 | CCNT1 (0.32) | MAPTPGRNR3C2CCNT1CCNE1 | |
| SCHEMBL12906309 | 0.70 | CDK8 (0.42) | CYP1A2KDM4EALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL513464 | 0.68 | ESRRA (0.36) | POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL469899 | 0.67 | GSK3B (0.46) | CYP3A4CYP1A2HPGDPOLBKDM4E | |
| SCHEMBL20695057 | 0.66 | POLB (0.33) | POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15353202 | 0.66 | SIRT2 (0.46) | CYP3A4CYP1A2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1679935 | 0.65 | CSF1R (0.35) | POLBKDM4EALDH1A1MAPT | |
| SCHEMBL18797608 | 0.64 | CDK8 (0.40) | HPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL469883 | 0.63 | NPC1 (0.35) | CYP3A4CYP1A2HPGDPOLBKDM4E | |
| SCHEMBL24715944 | 0.62 | ALDH1A1 (0.50) | CYP3A4CYP1A1CYP1A2HPGDCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | disclosed |
| CN-108495849-B | Pyridazinone herbicides | FMC公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10750743-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-08-25 | — | — | US | disclosed |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2018-11-22 | — | — | US | disclosed |
| EP-3368523-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017074992-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10750743-B2 | Pyridazinone herbicides | PRDX4, PRDX6, PDXK | CYP3A4 55/4885CYP1A1 19/4885CYP1A2 20/4885 |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX4, PRDX6, PDXK | CYP3A4 72/4885CYP1A1 35/4885CYP1A2 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.