Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844458 | 0.73 | KDM4E (0.39) | CDK8ACVR1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL514515 | 0.72 | CDK8 (0.35) | CDK8ACVR1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL22500189 | 0.70 | MAPT (0.38) | CDK8ACVR1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL18308883 | 0.69 | ADORA2A (0.32) | NMT1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL15353574 | 0.68 | GAA (0.32) | ALDH1A1RAB9A | |
| SCHEMBL12906309 | 0.67 | CDK8 (0.42) | CDK8ACVR1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15478679 | 0.67 | ADORA2A (0.31) | NMT1 | |
| SCHEMBL21737447 | 0.67 | FPR2 (0.32) | NMT1 | |
| SCHEMBL20695057 | 0.67 | POLB (0.33) | NMT1CDK8ACVR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL469902 | 0.66 | CRHR1 (0.34) | NMT1CDK8ACVR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230085307-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-03-16 | — | — | US | disclosed |
| CN-108884055-B | Pyridazinone compound or salt thereof, and herbicide containing same | 石原产业株式会社 | 2022-07-12 | — | — | CN | disclosed |
| EP-3949731-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE | Nissan Chemical Corporation (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-113825398-A | Pyridazinone compounds and herbicides | 日产化学株式会社 | 2021-12-21 | — | — | CN | disclosed |
| EP-3438095-B1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| WO-2020204112-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE | 日産化学株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3438095-A1 | PYRIDAZINONE-TYPE COMPOUND OR SALT THEREOF, AND HERBICIDE COMPRISING SAME | Ishihara Sangyo Kaisha, Ltd. (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | H1-0, H1-4, H1-3 | NMT1 2939/4885CDK8 3694/4885ACVR1 1577/4885 |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | NMT1 2490/4885CDK8 3755/4885ACVR1 1220/4885 |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | H1-0, H1-4, H1-3 | NMT1 2939/4885CDK8 3694/4885ACVR1 1577/4885 |
| US-20230085307-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE | H1-0, PDXK, H1-4 | NMT1 2909/4885CDK8 220/4885ACVR1 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.