Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679935 | 0.80 | CSF1R (0.35) | CSF1RKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL469635 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1CDK8ACVR1LMNA | |
| SCHEMBL3789703 | 0.71 | MAPK8 (0.38) | ALDH1A1CDK8ACVR1KMT2ALMNA | |
| SCHEMBL466412 | 0.69 | MAPT (0.36) | ALDH1A1CDK8ACVR1LMNASMN1; SMN2 | |
| SCHEMBL1679887 | 0.69 | ERCC1 (0.49) | KDM4EUSP2ALDH1A1TSHRCDK8 | |
| SCHEMBL6260037 | 0.69 | KDM4E (0.40) | CSF1RKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL10288222 | 0.68 | LMNA (0.33) | ALDH1A1CDK8ACVR1LMNASMN1; SMN2 | |
| SCHEMBL919364 | 0.68 | MAPT (0.38) | ALDH1A1TSHRCDK8ACVR1KMT2A | |
| SCHEMBL15935620 | 0.68 | ESR2 (0.42) | ALDH1A1CDK8ACVR1KMT2A | |
| SCHEMBL510530 | 0.68 | MAPK8 (0.36) | CSF1RKDM4ECDK8ACVR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045271-A1 | HERBICIDALLY ACTIVE, HETEROCYCLYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |