SCHEMBL16799415

SCHEMBL16799415

C=C(C)C(=O)NCCCNC(=O)CCCCCCCCN

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.52
PAOX Q6QHF9 4/20 0.49
KDM4A O75164 1/20 0.46
HIF1A Q16665 1/20 0.46
TET2 Q6N021 1/20 0.46
DOHH Q9BU89 1/20 0.46
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
FAAH O00519 3/20 0.42
DNM1 Q05193 2/20 0.41
CASP2 P42575 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16798860 1.00 SLC6A5 (0.52) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16799419 1.00 SLC6A5 (0.52) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16798876 1.00 SLC6A5 (0.52) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16799234 1.00 SLC6A5 (0.52) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16799073 0.98 SLC6A5 (0.50) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL17307120 0.95 SLC6A5 (0.54) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16309303 0.90 FAAH (0.46) SMN1; SMN2FAAHDNM1CASP2TSHR
SCHEMBL110911 0.86 PAOX (0.64) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL3508069 0.86 PAOX (0.64) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL16799464 0.85 ADRA1A (0.53) SLC6A5KDM4ELMNAFAAHDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3077476-B1 NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF NEXDOT (FR) 2020-02-12 EP disclosed
US-10465030-B2 Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof NEXDOT (FR) 2019-11-05 US disclosed
US-20160304648-A1 NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF NEXDOT (FR) 2016-10-20 US disclosed
EP-3077476-A1 NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF Nexdot (FR) 2016-10-12 EP disclosed
WO-2015082656-A1 NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF NEXDOT (FR) 2015-06-11 WO disclosed