Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19822715 | 0.77 | EPHX1 (0.37) | TDP1KDM4EKMT2AMEN1 | |
| SCHEMBL16800247 | 0.71 | SYK (0.43) | CTSSCTSKSYKL3MBTL1ATM | |
| SCHEMBL16800256 | 0.69 | ADRB2 (0.39) | CTSSCTSKNAMPTMAPTTDP1 | |
| SCHEMBL26031908 | 0.68 | NAMPT (0.41) | NAMPTMAPTTDP1KDM4EL3MBTL1 | |
| SCHEMBL21221563 | 0.68 | LOXL2 (0.46) | CTSSCTSKNAMPTMAPTTDP1 | |
| SCHEMBL7408378 | 0.68 | ATM (0.54) | CTSSCTSKSYKKMT2AATM | |
| SCHEMBL23640555 | 0.67 | KDM4E (0.48) | MAPTTDP1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL24124249 | 0.66 | NAMPT (0.53) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL13109024 | 0.65 | ATM (0.54) | CTSSCTSKSYKATM | |
| SCHEMBL6835510 | 0.65 | ATM (0.54) | CTSSCTSKSYKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |