Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640556 | 0.80 | KDM4E (0.48) | KDM4EPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL24575404 | 0.80 | KDM4E (0.48) | KDM4EPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL10526489 | 0.78 | KDM4E (0.43) | KDM4EALOX15GAAMAPTALDH1A1 | |
| SCHEMBL16800280 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3453665 | 0.68 | KDM1A (0.55) | KDM4EPOLBALOX15ALDH1A1HPGD | |
| SCHEMBL12204742 | 0.68 | ACHE (0.59) | KDM4EPOLBGAAMAPTALDH1A1 | |
| SCHEMBL8165902 | 0.68 | KDM4E (0.46) | KDM4EGAAALDH1A1TDP1MEN1 | |
| SCHEMBL8620807 | 0.68 | KDM4E (0.43) | KDM4EPOLBALOX15GAAMAPT | |
| SCHEMBL15325738 | 0.67 | ACHE (0.58) | POLBGAAMAPTALDH1A1ACHE | |
| SCHEMBL10523659 | 0.66 | ALDH1A1 (0.43) | KDM4EPOLBALOX15MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214542-A1 | NOVEL AMINE FUNCTIONALIZED POLYMERS AND METHODS OF PREPARATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-07-15 | — | — | US | disclosed |