Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.30 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.30 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798942 | 0.89 | GRM5 (0.37) | GRM5HSD11B1MEN1CYP2C9KMT2A | |
| SCHEMBL16801056 | 0.87 | CCR2 (0.40) | GRM5HSD11B1MEN1KMT2A | |
| SCHEMBL16800949 | 0.86 | GRM5 (0.36) | GRM5HSD11B1ALDH1A1ESR1ESR2 | |
| SCHEMBL16799547 | 0.86 | GRM5 (0.36) | GRM5HSD11B1 | |
| SCHEMBL16800950 | 0.85 | DRD1 (0.37) | GRM5ESR1ESR2 | |
| SCHEMBL16800681 | 0.84 | MAPT (0.38) | GRM5MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL16799325 | 0.84 | GRM5 (0.41) | GRM5MEN1KMT2A | |
| SCHEMBL16800806 | 0.83 | CYP11B2 (0.36) | GRM5HSD11B1CYP11B1CYP11B2 | |
| SCHEMBL16799448 | 0.83 | CYP11B2 (0.40) | GRM5CYP11B1CYP11B2RAB9A | |
| SCHEMBL16799577 | 0.83 | GRM5 (0.34) | GRM5CYP11B2ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015083130-A1 | FUSED PYRIDINE AND PYRIMIDINE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-06-11 | — | — | WO | disclosed |