Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 3/20 | 0.53 |
| ▸ | GABRD | O14764 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.53 |
| ▸ | GABRE | P78334 | 3/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511489 | 0.87 | NPSR1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL17637791 | 0.87 | NPSR1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL10357156 | 0.87 | NPSR1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL16797962 | 0.85 | NPSR1 (0.64) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL67700 | 0.80 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2KMT2AGABRP | |
| SCHEMBL635182 | 0.80 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2KMT2AGABRP | |
| SCHEMBL29886872 | 0.80 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2KMT2AGABRP | |
| SCHEMBL16925876 | 0.80 | ESR2 (0.52) | SMN1; SMN2KMT2AMAPK1CA9CA12 | |
| SCHEMBL21824208 | 0.79 | GABRP (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL6255392 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-11641775-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| US-11641775-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| US-11056652-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2021-07-06 | — | — | US | disclosed |
| US-20210151682-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10944058-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| EP-3693437-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2020-08-12 | — | — | EP | disclosed |
| EP-3345984-B1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |
| US-20190288209-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
| US-20180097178-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
| US-20180097178-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
| EP-3077477-B1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-9882142-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9882142-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20160301005-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160301005-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20150179940-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150179940-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| WO-2015082056-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10944058-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-11056652-B2 | Compounds and organic electronic devices | ETV6, AFF2, CYP2C19 | NPC1 1240/4885RAB9A 932/4885SMN1; SMN2 3031/4885 |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-20210151682-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-11641775-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-20190288209-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, AFF2, CYP2C19 | NPC1 1240/4885RAB9A 932/4885SMN1; SMN2 3031/4885 |
| US-20180097178-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-20150179940-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | NPC1 1165/4885RAB9A 1003/4885SMN1; SMN2 3110/4885 |
| US-20160301005-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, AFF2, CYP2C19 | NPC1 1240/4885RAB9A 932/4885SMN1; SMN2 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.