Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29969329 | 0.91 | SLC7A5 (0.53) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL6523945 | 0.89 | SLC7A5 (0.57) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL168029 | 0.89 | SLC7A5 (0.57) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL29969049 | 0.88 | SLC7A5 (0.50) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL25234890 | 0.87 | SLC7A5 (0.56) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL3476198 | 0.87 | SLC7A5 (0.56) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL4453960 | 0.82 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL27680265 | 0.82 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL27725763 | 0.82 | SLC7A5 (0.54) | SLC7A5TAAR1HDAC8ALPIPKM | |
| SCHEMBL8012238 | 0.81 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059739-B2 | Non-benzenoid aromatic systems for imaging, monitoring and therapy | MEDIBEACON INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20160083426-A1 | NON-BENZENOID AROMATIC SYSTEMS FOR IMAGING, MONITORING AND THERAPY | MEDIBEACON INC. (US) | 2016-03-24 | — | — | US | disclosed |
| US-9226980-B2 | Azulene and azaazulene systems for imaging, monitoring and therapy | MEDIBEACON INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-9186349-B2 | Diaza heterocyclic compounds for phototherapy | MALLINCKRODT LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-8731655-B2 | Compounds containing acyclic N-N bonds for phototherapy | MALLINCKRODT LLC (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120289884-A1 | Fused Ring Diarylamino Photosensitizers for Phototherapy | MALLINCKRODT LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120203102-A1 | AZULENE AND AZAAZULENE SYSTEMS FOR IMAGING, MONITORING AND THERAPY | MALLINCKRODT LLC (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120058954-A1 | Diaza Heterocyclic Compounds for Phototherapy | OCERA THERAPEUTICS LLC | 2012-03-08 | — | — | US | disclosed |
| US-20120053511-A1 | Compounds Containing Acyclic N-N Bonds for Phototherapy | MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.) | 2012-03-01 | — | — | US | disclosed |
| US-20110288033-A1 | Disulfide Compounds for Phototherapy | MALLINCKRODT INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110264026-A1 | Azo Derivatives and Uses Thereof in Phototherapy | MALLINCKRODT LLC | 2011-10-27 | — | — | US | disclosed |
| WO-2011084571-A2 | AZIDE DERIVATIVES FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011060113-A1 | SULFENAMIDE COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011031915-A2 | NON-BENZENOID AROMATIC SYSTEMS FOR IMAGING, MONITORING AND THERAPY | MALLINCKRODT INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| WO-2010132525-A1 | COMPOUNDS CONTAINING ACYCLIC N-O BONDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132554-A2 | DIAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132547-A2 | OXAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132515-A1 | COMPOUNDS CONTAINING ACYCLIC N-N BONDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| EP-2227474-A1 | AZO AND DIAZA DERIVATIVES AND USES THEREOF IN PHOTOTHERAPY | Mallinckrodt Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2010060018-A1 | AZO AND DIAZA DERIVATIVES AND USES THEREOF IN PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288033-A1 | Disulfide Compounds for Phototherapy | SPIN1, QSOX1, SAV1 | SLC7A5 1450/4885TAAR1 3060/4885SLC6A2 3362/4885 |
| US-20110264026-A1 | Azo Derivatives and Uses Thereof in Phototherapy | IRAK1, IL1A, MALT1 | SLC7A5 4004/4885TAAR1 4076/4885SLC6A2 4874/4885 |
| US-20120058954-A1 | Diaza Heterocyclic Compounds for Phototherapy | BAD, BID, CASP3 | SLC7A5 3999/4885TAAR1 4775/4885SLC6A2 4419/4885 |
| US-20120203102-A1 | AZULENE AND AZAAZULENE SYSTEMS FOR IMAGING, MONITORING AND THERAPY | AZI2, ALK, ZKSCAN2 | SLC7A5 726/4885TAAR1 491/4885SLC6A2 2159/4885 |
| US-20160083426-A1 | NON-BENZENOID AROMATIC SYSTEMS FOR IMAGING, MONITORING AND THERAPY | PAH, AHR, ALK | SLC7A5 1091/4885TAAR1 779/4885SLC6A2 728/4885 |
| US-10059739-B2 | Non-benzenoid aromatic systems for imaging, monitoring and therapy | PAH, AHR, ALK | SLC7A5 1091/4885TAAR1 779/4885SLC6A2 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.