SCHEMBL1680321

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6185799	0.84	PLK1 (0.50)	PLK1ALOX15HTTEGLN1HDAC1
	SCHEMBL17514250	0.82	TAS1R3 (0.69)	PLK1TAS1R3TAS1R1
	SCHEMBL6185796	0.82	TAS1R3 (0.69)	PLK1TAS1R3TAS1R1
	SCHEMBL2575332	0.81	ALOX15 (0.66)	PLK1ALOX15HTTEGLN1HDAC1
	SCHEMBL16621111	0.81	PLK1 (0.66)	PLK1ALOX15HTTEGLN1HDAC1
	SCHEMBL17634217	0.81	PLK1 (0.65)	PLK1ALOX15HTTEGLN1HDAC1
	SCHEMBL13382886	0.81	PLK1 (0.65)	PLK1ALOX15HTTEGLN1HDAC1
	SCHEMBL24219845	0.80	PLK1 (0.64)	PLK1ALOX15HTTHDAC1HDAC2
	SCHEMBL11962154	0.80	PLK1 (1.00)	PLK1ALOX15HTTHDAC1HDAC2
	SCHEMBL3492806	0.80	PLK1 (0.72)	PLK1ALOX15HTTHDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.