Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807098 | 0.99 | IGF1R (0.43) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807064 | 0.96 | RARB (0.44) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807094 | 0.94 | BACE1 (0.42) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807070 | 0.94 | IGF1R (0.44) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807126 | 0.92 | RARB (0.46) | RARBBCHEIGF1RALOX15FFAR1 | |
| SCHEMBL16807108 | 0.92 | BCHE (0.45) | RARBBCHEBACE1ALOX5CA2 | |
| SCHEMBL16807134 | 0.90 | RARB (0.44) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807072 | 0.90 | BACE1 (0.43) | RARBBCHEIGF1RALOX15BACE1 | |
| SCHEMBL16807104 | 0.90 | BCHE (0.43) | RARBBCHEBACE1ALOX5CA2 | |
| SCHEMBL16807106 | 0.89 | ALOX5 (0.47) | RARBBCHEALOX5CA2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |