SCHEMBL16807108

SCHEMBL16807108

CCc1ccc(-c2ccc(-c3ccc(CCCCCO)cc3CC)cc2CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.45
RARB P10826 6/20 0.42
CYP4F2 P78329 3/20 0.41
CYP4A11 Q02928 3/20 0.41
ALOX5 P09917 1/20 0.39
CA2 P00918 1/20 0.39
ACHE P22303 2/20 0.38
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
P2RY12 Q9H244 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
RARA P10276 1/20 0.37
MAPT P10636 1/20 0.37
MTOR P42345 1/20 0.37
KMT2A Q03164 1/20 0.37
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807104 0.98 BCHE (0.43) BCHERARBCYP4F2CYP4A11ALOX5
SCHEMBL16807091 0.95 BCHE (0.46) BCHERARBCYP4F2CYP4A11CA2
SCHEMBL16807113 0.94 CYP4A11 (0.41) BCHERARBCYP4F2CYP4A11ALOX5
SCHEMBL16807069 0.94 BCHE (0.43) BCHERARBCYP4F2CYP4A11CA2
SCHEMBL16807128 0.92 RARB (0.52) BCHERARBACHEMEN1ALDH1A1
SCHEMBL16807106 0.92 ALOX5 (0.47) BCHERARBCYP4F2CYP4A11ALOX5
SCHEMBL16807103 0.92 RARB (0.43) BCHERARBCYP4F2CYP4A11ALOX5
SCHEMBL16807118 0.92 RARB (0.49) BCHERARBACHEMEN1ALDH1A1
SCHEMBL16807117 0.92 RARB (0.52) BCHERARBACHEMEN1ALDH1A1
SCHEMBL16807133 0.92 RARB (0.52) BCHERARBACHEMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed