SCHEMBL16807104

SCHEMBL16807104

CCc1ccc(-c2ccc(-c3ccc(CCCCO)cc3CC)cc2CC)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.43
CYP4A11 Q02928 4/20 0.42
CYP4F2 P78329 3/20 0.42
RARB P10826 3/20 0.40
ALOX5 P09917 1/20 0.40
CA2 P00918 2/20 0.37
BACE1 P56817 1/20 0.37
RORC P51449 1/20 0.36
ACHE P22303 2/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
P2RY12 Q9H244 1/20 0.36
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807108 0.98 BCHE (0.45) BCHECYP4A11CYP4F2RARBALOX5
SCHEMBL16807069 0.95 BCHE (0.43) BCHECYP4A11CYP4F2RARBCA2
SCHEMBL16807113 0.95 CYP4A11 (0.41) BCHECYP4A11CYP4F2RARBALOX5
SCHEMBL16807091 0.94 BCHE (0.46) BCHECYP4A11CYP4F2RARBCA2
SCHEMBL16807105 0.91 ALOX5 (0.48) BCHECYP4A11CYP4F2RARBALOX5
SCHEMBL16807122 0.91 RARB (0.47) BCHECYP4A11CYP4F2RARBALOX5
SCHEMBL16807115 0.91 RARB (0.50) RARBALOX5ACHEEGFR
SCHEMBL16807098 0.91 IGF1R (0.43) BCHECYP4A11CYP4F2RARBALOX5
SCHEMBL16807135 0.91 CYP4A11 (0.45) BCHECYP4A11CYP4F2RARBCA2
SCHEMBL16807081 0.91 CYP4A11 (0.42) BCHECYP4A11CYP4F2RARBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed