SCHEMBL16807113

SCHEMBL16807113

CCc1ccc(-c2ccc(-c3ccc(CCCO)cc3CC)cc2CC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 4/20 0.41
CYP4F2 P78329 3/20 0.41
ALOX5 P09917 3/20 0.41
BACE1 P56817 1/20 0.38
RARB P10826 2/20 0.38
BCHE P06276 1/20 0.38
RORC P51449 1/20 0.37
EGFR P00533 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
CA2 P00918 1/20 0.36
MMP2 P08253 2/20 0.35
MMP3 P08254 1/20 0.35
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
P2RY12 Q9H244 1/20 0.35
PRKAB2 O43741 1/20 0.35
PRKAG1 P54619 1/20 0.35
PRKAA2 P54646 1/20 0.35
PRKAA1 Q13131 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807104 0.95 BCHE (0.43) CYP4A11CYP4F2ALOX5BACE1RARB
SCHEMBL16807081 0.95 CYP4A11 (0.42) CYP4A11CYP4F2BACE1RARBBCHE
SCHEMBL16807108 0.94 BCHE (0.45) CYP4A11CYP4F2ALOX5BACE1RARB
SCHEMBL16807094 0.91 BACE1 (0.42) CYP4A11CYP4F2ALOX5BACE1RARB
SCHEMBL16807107 0.91 ALOX5 (0.49) CYP4A11CYP4F2ALOX5BACE1RARB
SCHEMBL16807116 0.91 RARB (0.45) CYP4A11ALOX5RARBCA2
SCHEMBL16807069 0.91 BCHE (0.43) CYP4A11CYP4F2BACE1RARBBCHE
SCHEMBL16807143 0.91 CYP4A11 (0.44) CYP4A11CYP4F2RARBCA2PRKAB2
SCHEMBL16807111 0.90 ALOX5 (0.43) CYP4A11CYP4F2ALOX5BACE1RORC
SCHEMBL16807121 0.90 RARB (0.50) ALOX5RARBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed