SCHEMBL16807169

SCHEMBL16807169

CCCc1ccc(CCc2ccc(-c3ccc(CCO)cc3CC)c(CC)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
BACE1 P56817 2/20 0.41
ALOX5 P09917 2/20 0.41
TSHR P16473 1/20 0.41
VDR P11473 2/20 0.40
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
CA2 P00918 3/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
PLK1 P53350 1/20 0.39
THRB P10828 1/20 0.38
PDK2 Q15119 1/20 0.37
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15725328 0.92 ALOX5 (0.46) CNR1CNR2BACE1ALOX5TSHR
SCHEMBL16807165 0.91 BACE1 (0.42) BACE1ALOX5TSHRVDRCYP4F2
SCHEMBL16807076 0.90 ALOX5 (0.45) CNR1CNR2BACE1ALOX5TSHR
SCHEMBL16807170 0.90 ALDH1A1 (0.45) KDM4EALDH1A1GPR84CA2PLK1
SCHEMBL16807171 0.90 CNR1 (0.43) CNR1CNR2BACE1ALOX5VDR
SCHEMBL16807175 0.90 CNR1 (0.46) CNR1CNR2BACE1ALOX5VDR
SCHEMBL16807110 0.89 ALOX5 (0.51) CNR1CNR2BACE1ALOX5TSHR
SCHEMBL16807173 0.89 BCHE (0.43) CNR1CNR2BACE1ALOX5VDR
SCHEMBL16774551 0.89 RARB (0.47) KDM4EALDH1A1LPLLIPG
SCHEMBL16807160 0.88 CYP4F2 (0.42) BACE1ALOX5TSHRVDRCYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed