SCHEMBL16807175

SCHEMBL16807175

CCCc1ccc(CCc2ccc(-c3ccc(CO)cc3CC)c(CC)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
VDR P11473 2/20 0.43
BACE1 P56817 1/20 0.41
ALOX5 P09917 2/20 0.41
GPR84 Q9NQS5 1/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
PLK1 P53350 1/20 0.39
THRB P10828 2/20 0.38
PDK2 Q15119 1/20 0.37
CA2 P00918 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MCL1 Q07820 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
MAOA P21397 1/20 0.35
MGLL Q99685 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807163 0.91 BACE1 (0.42) CNR1CNR2VDRBACE1GPR84
SCHEMBL16807177 0.90 ALDH1A1 (0.45) GPR84PLK1THRBCA2
SCHEMBL15725352 0.90 ALOX5 (0.44) CNR1CNR2BACE1ALOX5GPR84
SCHEMBL16807169 0.90 CNR1 (0.46) CNR1CNR2VDRBACE1ALOX5
SCHEMBL16807182 0.89 RARB (0.47) CNR2LPLLIPG
SCHEMBL16807164 0.88 DAO (0.43) VDRBACE1GPR84
SCHEMBL16807089 0.88 MCL1 (0.45) CNR1CNR2BACE1ALOX5LPL
SCHEMBL16807185 0.87 RARB (0.49) LPLLIPGMGLL
SCHEMBL16807112 0.87 ALOX5 (0.49) CNR1CNR2VDRBACE1ALOX5
SCHEMBL16807171 0.87 CNR1 (0.43) CNR1CNR2VDRBACE1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed