SCHEMBL1680774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680398	0.90	MAPK8 (0.40)	ALDH1A1L3MBTL1HPGDGAAHTT
	SCHEMBL1680258	0.88	MAPK8 (0.39)	ALDH1A1L3MBTL1HPGDGAAHTT
	SCHEMBL1680833	0.88	PTGER4 (0.42)	PTGER4ALDH1A1L3MBTL1HPGDMAPK8
	SCHEMBL920728	0.88	PTGER4 (0.44)	PTGER4PTGER2MAPK8MAPK14MET
	SCHEMBL1680879	0.86	MAPK8 (0.42)	PTGER4PTGER2ALDH1A1L3MBTL1HPGD
	SCHEMBL1680626	0.84	FFAR1 (0.42)	ALDH1A1HPGDHTTMAPK8TDP1
	SCHEMBL1681128	0.83	PIK3CD (0.44)	ALDH1A1L3MBTL1HPGDGAAHTT
	SCHEMBL1680415	0.83	MAPK8 (0.52)	ALDH1A1MAPK8PDPK1MAPK14
	SCHEMBL920809	0.82	PTGER4 (0.58)	PTGER4PTGER2ALDH1A1L3MBTL1HPGD
	SCHEMBL1680407	0.81	MAPK8 (0.40)	ALDH1A1L3MBTL1HPGDGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.