SCHEMBL1680398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680774	0.90	PTGER4 (0.42)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL920728	0.90	PTGER4 (0.44)	MAPK8MAPK14CA2CA4
	SCHEMBL1680833	0.90	PTGER4 (0.42)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL1680258	0.90	MAPK8 (0.39)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL1680626	0.86	FFAR1 (0.42)	MAPK8CA2CA4TDP1ALDH1A1
	SCHEMBL1681128	0.85	PIK3CD (0.44)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL1680415	0.85	MAPK8 (0.52)	MAPK8MAPK14ALDH1A1
	SCHEMBL1680856	0.81	ALDH1A1 (0.40)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL1680988	0.80	GALR3 (0.40)	MAPK8MAPK14CA2CA4TDP1
	SCHEMBL1680922	0.80	GALR3 (0.40)	MAPK8MAPK14CA2CA4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.