SCHEMBL1680835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680856	0.89	ALDH1A1 (0.40)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL1681092	0.88	KLKB1 (0.41)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL1680602	0.84	KMT2A (0.44)	KMT2ACYP3A4MAPK14PDPK1
	SCHEMBL921262	0.83	MAPK8 (0.38)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL921276	0.82	CYP3A4 (0.54)	LIPGMAPTKMT2ACYP3A4MAPK14
	SCHEMBL1681267	0.82	CYP1A2 (0.43)	LIPGKDM4EMEN1ALDH1A1MAPT
	SCHEMBL1680696	0.81	MAPK14 (0.46)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL921783	0.81	MMP13 (0.38)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL1680407	0.81	MAPK8 (0.40)	KDM4EMEN1ALDH1A1MAPTKMT2A
	SCHEMBL1680859	0.79	KLKB1 (0.40)	LIPGKDM4EALDH1A1CYP3A4MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.