SCHEMBL1680903

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14534346	0.90	MAP4K4 (0.32)	ADORA2AADORA1ADORA3ADORA2B
	SCHEMBL1680893	0.90	ADORA2A (0.42)	ADORA2AADORA1ADORA3ADORA2BKLKB1
	SCHEMBL922980	0.89	ADORA2A (0.38)	ADORA2AADORA1ADORA3ADORA2BKLKB1
	SCHEMBL920661	0.84	KDM4E (0.47)	KLKB1LMNAAPEX1MAPTHPGD
	SCHEMBL921649	0.84	KLKB1 (0.46)	KLKB1APEX1MAPTRXFP1HPGD
	SCHEMBL1680652	0.82	PDPK1 (0.44)	KLKB1HPGDALDH1A1
	SCHEMBL1680563	0.79	ALOX15 (0.35)	KLKB1MAPTHPGDKDM4EUSP2
	SCHEMBL14534355	0.79	ADORA2A (0.35)	ADORA2AADORA1ADORA3ADORA2BKLKB1
	SCHEMBL1681109	0.78	MAPK14 (0.38)	ADORA2AADORA1KLKB1LMNAHPGD
	SCHEMBL919566	0.78	PPARG (0.48)	LMNAAPEX1MAPTRXFP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.