SCHEMBL922980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680563	0.90	ALOX15 (0.35)	ALDH1A1MAPK14KLKB1MAPK8L3MBTL1
	SCHEMBL1680893	0.89	ADORA2A (0.42)	ADORA2AADORA1ADORA3ADORA2BALDH1A1
	SCHEMBL1680903	0.89	ADORA2A (0.39)	ADORA2AADORA1ADORA3ADORA2BALDH1A1
	SCHEMBL1681109	0.89	MAPK14 (0.38)	ADORA2AADORA1ALDH1A1MAPK14KLKB1
	SCHEMBL12360906	0.87	MAPK14 (0.35)	ALDH1A1MAPK14KLKB1MAPK8L3MBTL1
	SCHEMBL1681036	0.86	MAPK14 (0.36)	ALDH1A1MAPK14KLKB1MAPK8L3MBTL1
	SCHEMBL1680806	0.86	KDM4E (0.38)	ADORA2AALDH1A1KLKB1MAPK8HPGD
	SCHEMBL920425	0.86	KLKB1 (0.40)	ADORA2AADORA1ALDH1A1MAPK14KLKB1
	SCHEMBL1681098	0.86	TDP1 (0.37)	ALDH1A1MAPK14KLKB1MAPK8L3MBTL1
	SCHEMBL1680856	0.86	ALDH1A1 (0.40)	ADORA2AADORA1ALDH1A1MAPK14KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.