Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.62 |
| ▸ | RXRB | P28702 | 9/20 | 0.62 |
| ▸ | RXRG | P48443 | 5/20 | 0.62 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198911 | 0.97 | RXRA (0.57) | RXRARXRBRXRGTPMTHCAR1 | |
| SCHEMBL3082270 | 0.87 | RXRA (0.72) | RXRARXRBRXRGCES2DHODH | |
| SCHEMBL17048588 | 0.87 | RXRA (0.72) | RXRARXRBRXRGCES2DHODH | |
| SCHEMBL2926459 | 0.85 | TPMT (0.61) | RXRARXRBRXRGTPMTHCAR1 | |
| SCHEMBL30240792 | 0.85 | TPMT (0.61) | RXRARXRBRXRGTPMTHCAR1 | |
| SCHEMBL17231196 | 0.83 | TPMT (0.76) | RXRARXRBTPMTHCAR1DHODH | |
| SCHEMBL26375464 | 0.79 | NOTUM (0.50) | RXRARXRBRXRGCES2 | |
| SCHEMBL503980 | 0.79 | CES2 (0.70) | RXRARXRBRXRGMRGPRX4CES2 | |
| SCHEMBL12583263 | 0.79 | RAPGEF4 (0.48) | RXRARXRBRXRGCES2 | |
| SCHEMBL30469526 | 0.77 | RXRA (0.74) | RXRARXRBRXRGDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087062-A1 | COMPLEXES AND CATALYTIC PROCESSES | THE UNIVERSITY OF SUSSEX (GB) | 2015-06-18 | — | — | WO | disclosed |