Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | XPO1 | O14980 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949153 | 0.98 | NOTUM (0.49) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL12583213 | 0.95 | NOTUM (0.50) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL26375464 | 0.95 | NOTUM (0.50) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL15497368 | 0.88 | RXRA (0.46) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL13866628 | 0.87 | RXRA (0.52) | RAPGEF4RXRARXRBRXRGIKBKB | |
| SCHEMBL24211025 | 0.86 | RXRA (0.50) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL24211077 | 0.86 | RXRA (0.50) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL29319679 | 0.85 | ALDH1A1 (0.46) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL26821716 | 0.84 | RXRA (0.47) | RAPGEF4NOTUMRXRARXRBRXRG | |
| SCHEMBL15704675 | 0.84 | RXRA (0.39) | RAPGEF4NOTUMRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-1712549-B1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO LTD (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, BCAT2, AADAT | RAPGEF4 4653/4885NOTUM 842/4885RXRA 4512/4885 |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | AADAT, BCAT2, BCAT1 | RAPGEF4 3529/4885NOTUM 2636/4885RXRA 4794/4885 |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, AADAT, BCAT2 | RAPGEF4 4605/4885NOTUM 877/4885RXRA 4273/4885 |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | RAPGEF4 2769/4885NOTUM 2913/4885RXRA 3881/4885 |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | BCAT1, BCAT2, AADAT | RAPGEF4 4653/4885NOTUM 842/4885RXRA 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.