Sitosteryl Acetate

Sitosteryl Acetate

SCHEMBL168092

CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.73
TDP1 Q9NUW8 2/20 0.73
TSHR P16473 1/20 0.73
F2 P00734 1/20 0.73
DPP4 P27487 1/20 0.73
CYP1A2 P05177 1/20 0.69
CTSD P07339 1/20 0.66
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
POLA1 P09884 1/20 0.60
NPC1 O15118 1/20 0.60
CYP46A1 Q9Y6A2 1/20 0.59
NR1H3 Q13133 4/20 0.58
GRIN1 Q05586 3/20 0.58
GRIN2A Q12879 3/20 0.58
GRIN2B Q13224 3/20 0.58
EPHA2 P29317 3/20 0.58
OSBP P22059 2/20 0.58
RORC P51449 1/20 0.58
OSBP2 Q969R2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sitosteryl Acetate SCHEMBL25679307 1.00 POLB (0.73) POLBTDP1TSHRF2DPP4
SCHEMBL19581467 0.92 POLB (0.72) POLBTDP1TSHRF2DPP4
SCHEMBL32671059 0.92 POLB (0.72) POLBTDP1TSHRF2DPP4
SCHEMBL4736527 0.92 POLB (0.72) POLBTDP1TSHRF2DPP4
SCHEMBL19581466 0.92 POLB (0.72) POLBTDP1TSHRF2DPP4
SCHEMBL24015445 0.92 POLB (0.72) POLBTDP1TSHRF2DPP4
SCHEMBL24015354 0.92 POLB (0.71) POLBTDP1TSHRF2DPP4
SCHEMBL25352872 0.91 POLB (0.70) POLBTDP1TSHRF2DPP4
SCHEMBL25358326 0.91 POLB (0.70) POLBTDP1TSHRF2DPP4
SCHEMBL25358335 0.91 POLB (0.70) POLBTDP1TSHRF2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119997933-A Oral pharmaceutical composition containing taxane and preparation method thereof 韩国科学技术研究院 2025-05-13 CN claimed
CN-118717785-B Pharmaceutical composition for preventing and treating scar hyperplasia and preparation method and application thereof 威海人生药业有限公司 2025-03-28 CN claimed
CN-118717785-A Pharmaceutical composition for preventing and treating scar hyperplasia and preparation method and application thereof 威海人生药业有限公司 2024-10-01 CN claimed
CN-118593390-A Tricholoma matsutake extract with whitening effect and preparation method thereof 云南英格生物技术有限公司 2024-09-06 CN claimed
WO-2024076056-A1 ORAL PHARMACEUTICAL COMPOSITION CONTAINING TAXANE AND PREPARATION METHOD THEREFOR 한국과학기술연구원 2024-04-11 WO claimed
CN-117502321-A Method for screening apocynum venetum oxytocin and application of oxytocin 滨州市海洋发展研究院 2024-02-06 CN claimed
CN-114354774-A Detection method of fingerprint of corn oil unsaponifiable matter and standard fingerprint thereof 湖南天龙制药有限公司 2022-04-15 CN claimed
CN-114306547-A Traditional Chinese medicine formula for regulating and controlling intestinal function of pregnant women 华子昂 2022-04-12 CN claimed
CN-112999158-B Preparation method and application of policosanol nano-liposome 江西省科学院生物资源研究所 2022-04-01 CN claimed
CN-112999158-A Preparation method and application of policosanol nano-liposome 江西省科学院生物资源研究所 2021-06-22 CN claimed
US-20260091072-A1 FOOD PRODUCTS COMPRISING OXALIC ACID- OR OXALATE-FREE INONOTUS OBLIQUUS EXTRACT THE BETTER FOR YOU COMPANY, LLC (US) 2026-04-02 US disclosed
EP-4704600-A1 DAIRY BEVERAGES WITH IMPROVED TASTE The Coca-Cola Company (US) 2026-03-11 EP disclosed
EP-4704601-A1 DAIRY-ALTERNATIVE BEVERAGES WITH IMPROVED TASTE The Coca-Cola Company (US) 2026-03-11 EP disclosed
US-20260055130-A1 METHODS FOR PURIFYING STEVIOL GLYCOSIDES AND USES OF THE SAME PURECIRCLE SDN BHD (MY) 2026-02-26 US disclosed
US-12557831-B2 Mogrosides and uses of the same THE COCA-COLA COMPANY (US) 2026-02-24 US disclosed
US-5958913-A ADMINISTERING SATURATED STEROL FATTY ACID ESTER RAISIO BENECOL LTD. (FI) 1999-09-28 US disclosed
EP-0594612-B1 A SUBSTANCE FOR LOWERING HIGH CHOLESTEROL LEVEL IN SERUM AND A METHOD FOR PREPARING THE SAME RAISION TEHTAAT OY AB (FI) 1997-08-06 EP disclosed
US-5502045-A REDUCING ABSORPTION OF CHOLESTEROL IN BLOOD USING SITOSTANOL FATTY ESTER RAISION TEHTAAT OY AB (FI) 1996-03-26 US disclosed
EP-0594612-A1 A SUBSTANCE FOR LOWERING HIGH CHOLESTEROL LEVEL IN SERUM AND A METHOD FOR PREPARING THE SAME. RAISION MARGARIINI OY (FI) 1994-05-04 EP disclosed
WO-1992019640-A1 A SUBSTANCE FOR LOWERING HIGH CHOLESTEROL LEVEL IN SERUM AND A METHOD FOR PREPARING THE SAME RAISION MARGARIINI OY (FI) 1992-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12557831-B2 Mogrosides and uses of the same TAS2R40, TAS2R20, TAS2R10 POLB 4673/4885TDP1 4687/4885TSHR 2379/4885
US-20260055130-A1 METHODS FOR PURIFYING STEVIOL GLYCOSIDES AND USES OF THE SAME TAS2R7, TAS2R42, TAS2R31 POLB 3894/4885TDP1 1920/4885TSHR 1727/4885
US-20260091072-A1 FOOD PRODUCTS COMPRISING OXALIC ACID- OR OXALATE-FREE INONOTUS OBLIQUUS EXTRACT ORAI1, OTC, ORAI2 POLB 2983/4885TDP1 1765/4885TSHR 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.