Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | EDNRA | P25101 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832533 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CYP2C19LMNAGAAMAPT | |
| SCHEMBL4992745 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP2C19LMNAEDNRAGAA | |
| SCHEMBL5376348 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP2C19LMNAEDNRAGAA | |
| SCHEMBL18609631 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP2C19LMNATAS1R3TAS1R1 | |
| SCHEMBL16785346 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP2C19LMNATAS1R3TAS1R1 | |
| SCHEMBL29434324 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP2C19LMNATAS1R3TAS1R1 | |
| SCHEMBL4997834 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP2C19LMNAEDNRAGAA | |
| SCHEMBL4998200 | 0.80 | KMT2A (0.48) | ALDH1A1CYP2C19LMNAEDNRAGAA | |
| SCHEMBL7593216 | 0.79 | RAB9A (0.54) | ALDH1A1CYP2C19LMNAEDNRAGAA | |
| SCHEMBL7446886 | 0.79 | RAB9A (0.49) | ALDH1A1CYP2C19LMNAEDNRAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044198-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-02-16 | — | — | US | disclosed |
| US-9446393-B2 | Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150165429-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044198-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | SOD1, C9, PYM1 | ALDH1A1 1211/4885CYP2C19 1341/4885LMNA 1302/4885 |
| US-20150165429-A1 | TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS | SOD1, YWHAZ, L1CAM | ALDH1A1 1084/4885CYP2C19 1215/4885LMNA 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.