SCHEMBL1680988

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680939	0.85	GALR3 (0.41)	GALR3NR2F2LMNAMAPK1KLKB1
	SCHEMBL1680922	0.82	GALR3 (0.40)	GALR3NR2F2LMNAKLKB1MAPK8
	SCHEMBL1680856	0.81	ALDH1A1 (0.40)	GALR3NR2F2LMNAKLKB1MAPK8
	SCHEMBL1680775	0.81	PSMD14 (0.42)	LMNAMAPTALDH1A1HPGDSMN1; SMN2
	SCHEMBL920425	0.80	KLKB1 (0.40)	GALR3NR2F2MAPK1KLKB1MAPK8
	SCHEMBL1680398	0.80	MAPK8 (0.40)	GALR3NR2F2KLKB1MAPK8ALDH1A1
	SCHEMBL921262	0.80	MAPK8 (0.38)	GALR3NR2F2LMNAMAPK1KLKB1
	SCHEMBL1680407	0.80	MAPK8 (0.40)	GALR3NR2F2LMNAKLKB1MAPK8
	SCHEMBL1681244	0.79	SYK (0.38)	LMNAMAPK1MAPK8MAPTKMT2A
	SCHEMBL1680528	0.79	KDM4E (0.41)	GALR3NR2F2LMNAKLKB1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.