SCHEMBL1680994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1681068	0.85	HPGD (0.42)	NAMPTMAPK14HPGDSALDH1A1LMNA
	SCHEMBL1680775	0.82	PSMD14 (0.42)	MAPK14HPGDSALDH1A1LMNAHPGD
	SCHEMBL1680922	0.81	GALR3 (0.40)	NAMPTKLKB1JAK2MAP4K4CHEK2
	SCHEMBL1680902	0.78	SLC8A1 (0.49)	MAPK14ALDH1A1LMNAHPGD
	SCHEMBL1680509	0.78	EPHX2 (0.49)	MAPK14HPGDSALDH1A1LMNAHPGD
	SCHEMBL858436	0.78	NAMPT (0.79)	NAMPTKLKB1JAK2MAP4K4CHEK2
	SCHEMBL1680549	0.78	ALDH1A1 (0.41)	MAPK14HPGDSALDH1A1LMNAHPGD
	SCHEMBL1680847	0.78	NNMT (0.43)	MAPK14ALDH1A1LMNA
	SCHEMBL1681352	0.77	MAPK14 (0.49)	NAMPTMAPK14ALDH1A1
	SCHEMBL12808405	0.77	MAPK14 (0.40)	MAPK14HPGDSALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.