Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812979 | 0.89 | CHRM4 (0.59) | CHRM4DRD2HTR7ALDH1A1GSK3B | |
| SCHEMBL16813021 | 0.88 | CHRM4 (0.51) | CHRM4DRD2HTR7ALDH1A1LMNA | |
| SCHEMBL16813036 | 0.85 | CNR1 (0.56) | ALDH1A1MAPTCNR1NTSR1OPRK1 | |
| SCHEMBL16796669 | 0.85 | CNR1 (0.43) | CNR1NTSR1OPRK1PDE4DGSK3B | |
| SCHEMBL16812971 | 0.84 | ALDH1A1 (0.62) | CHRM4DRD2HTR7ALDH1A1MAPT | |
| SCHEMBL16796592 | 0.83 | PTGS2 (0.49) | CNR1NTSR1OPRK1PDE4DGSK3B | |
| SCHEMBL16812983 | 0.81 | CNR1 (0.47) | CHRM4DRD2HTR7MAPTLMNA | |
| SCHEMBL16812975 | 0.81 | GSK3B (0.45) | CNR1NTSR1OPRK1PDE4DGSK3B | |
| SCHEMBL16813009 | 0.80 | GSK3B (0.43) | LMNACNR1NTSR1OPRK1PDE4D | |
| SCHEMBL16796600 | 0.78 | CHRM4 (0.46) | CHRM4DRD2HTR7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |