Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 7/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812975 | 0.84 | GSK3B (0.45) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813036 | 0.82 | CNR1 (0.56) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16796669 | 0.78 | CNR1 (0.43) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813014 | 0.78 | CHRM4 (0.51) | GSK3BCNR1NTSR1OPRK1PDE4D | |
| SCHEMBL16796592 | 0.77 | PTGS2 (0.49) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16812984 | 0.76 | CNR1 (0.47) | CCNB2CDK1CCNB1CCNB3CNR1 | |
| SCHEMBL16813015 | 0.74 | LMNA (0.60) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813041 | 0.73 | HPGD (0.47) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16812983 | 0.73 | CNR1 (0.47) | GSK3BGSK3ACNR1NTSR1OPRK1 | |
| SCHEMBL16813038 | 0.73 | CNR1 (0.56) | CNR1NTSR1OPRK1PDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |