SCHEMBL1681822

SCHEMBL1681822

C=CC(=O)NCCC1CO1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
TGM2 P21980 5/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379484 0.89 ZDHHC20 (0.49) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379986 0.87 ZDHHC20 (0.51) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379703 0.86 ZDHHC20 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379495 0.86 ZDHHC20 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379499 0.86 ZDHHC20 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379738 0.86 ZDHHC20 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20379480 0.86 ZDHHC20 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL368274 0.81 USP2 (0.44) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL9435786 0.81 ALDH1A1 (0.45) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL183843 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 US disclosed
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
US-9845385-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-12-19 US disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2674457-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
EP-3064546-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2016-09-07 EP disclosed
EP-2708576-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-08-24 EP disclosed
US-4496672-A Process for coating an electrically conductive substrate BASF FARBEN & FASERN A.G. (DE) 1985-01-29 US disclosed
EP-0052831-B1 PROCESS FOR COATING AN ELECTRICALLY CONDUCTIVE SUBSTRATE BASF Lacke + Farben AG (DE) 1983-12-14 EP disclosed
US-4416753-A USING DISPERSION OF CATIONIC RESIN AND IONIC PLASTIC BASF FARBEN & FASERN AG (DE) 1983-11-22 US disclosed
EP-0054193-B1 PROCESS FOR PREPARING A COATING BASF Lacke + Farben AG (DE) 1983-11-02 EP disclosed
EP-0036471-B1 PROCESS FOR THE ELECTROPHORETIC DEPOSITION OF A COATING ON AN ELECTRIC CONDUCTING WORKPIECE ACTING AS THE CATHODE BASF Lacke + Farben AG (DE) 1983-06-29 EP disclosed
EP-0054193-A1 Process for preparing a coating BASF Lacke + Farben AG (DE) 1982-06-23 EP disclosed
EP-0052831-A1 Process for coating an electrically conductive substrate BASF Lacke + Farben AG (DE) 1982-06-02 EP disclosed
EP-0036471-A1 Process for the electrophoretic deposition of a coating on an electric conducting workpiece acting as the cathode BASF Lacke + Farben AG (DE) 1981-09-30 EP disclosed
US-4208261-A POWDER COATING SHINTO PAINT CO., LTD. (JP) 1980-06-17 US disclosed
US-4156040-A Coagulation coating process FORD MOTOR COMPANY (US) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B ALDH1A1 2283/4885TSHR 4275/4885MAPK1 4819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.