Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173484 | 0.89 | CYP1A2 (0.42) | HKDC1KCNA5TRPM8KMT2AMEN1 | |
| SCHEMBL28054964 | 0.73 | ALOX5 (0.49) | HKDC1TRPM8KMT2AMEN1LMNA | |
| SCHEMBL2830117 | 0.70 | CA14 (0.39) | SLC1A3SLC1A2SLC1A1KDM4ECA12 | |
| SCHEMBL12305036 | 0.69 | ALDH1A1 (0.50) | KMT2AMEN1LMNAPOLBALDH1A1 | |
| SCHEMBL9998967 | 0.69 | SLC1A3 (0.34) | KMT2AMEN1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11050985 | 0.68 | HKDC1 (0.46) | HKDC1KMT2AMEN1LMNAHPGD | |
| SCHEMBL16886917 | 0.67 | CYP3A4 (0.53) | POLBALDH1A1MAPTCA12CA7 | |
| SCHEMBL16886918 | 0.67 | CYP3A4 (0.53) | POLBALDH1A1MAPTCA12CA7 | |
| SCHEMBL19902141 | 0.67 | CYP3A4 (0.53) | POLBALDH1A1MAPTCA12CA7 | |
| SCHEMBL14430040 | 0.67 | HKDC1 (0.41) | HKDC1KMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240090503-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2024-03-21 | — | — | US | disclosed |
| US-20230165251-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | FMC CORPORATION | 2023-06-01 | — | — | US | disclosed |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| EP-4117432-A2 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION (US) | 2023-01-18 | — | — | EP | disclosed |
| WO-2021183707-A2 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | HKDC1 4227/4885KCNA5 603/4885TRPM8 2867/4885 |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | CYP1B1, CYP4B1, TH | HKDC1 4080/4885KCNA5 589/4885TRPM8 2402/4885 |
| US-20240090503-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | NOX1, TH, NOX3 | HKDC1 4304/4885KCNA5 1765/4885TRPM8 3351/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | HKDC1 4227/4885KCNA5 603/4885TRPM8 2867/4885 |
| US-20230165251-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | NAT1, TH, Q6ZSR9 | HKDC1 4642/4885KCNA5 266/4885TRPM8 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.