Methacrylic Acid

Methacrylic Acid

SCHEMBL1682391

C=C(C)C(=O)O.OCC1=CCCCC1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 2/20 0.40
CYP1B1 Q16678 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.38
EPHX1 P07099 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316975 0.81
Acrylic Acid SCHEMBL3278734 0.81 TAAR1 (0.48) ALDH1A1ALOX15TAAR1SMN1; SMN2HPGD
Methacrylic Acid SCHEMBL30527835 0.81 KMT2A (0.35) ALDH1A1ALOX15TAAR1SMN1; SMN2HPGD
SCHEMBL1145650 0.79
SCHEMBL1145673 0.79 CXCR3 (0.42) ALDH1A1ALOX15TAAR1SMN1; SMN2EPHX1
SCHEMBL11065315 0.79 CXCR3 (0.42) ALDH1A1ALOX15TAAR1SMN1; SMN2EPHX1
SCHEMBL10882411 0.79 CXCR3 (0.42) ALDH1A1ALOX15TAAR1SMN1; SMN2EPHX1
Terephthalic Acid SCHEMBL8014758 0.77 GAA (0.50) ALDH1A1TAAR1SMN1; SMN2HPGDEPHX1
SCHEMBL2127670 0.77 ALDH1A1 (0.44) ALDH1A1ALOX15TAAR1SMN1; SMN2HPGD
Methacrylic Acid SCHEMBL1138615 0.77 ACMSD (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6150479-A CURABLE ADHESIVES FOR HEAT RESISTANCE LOCTITE CORPORATION (US) 2000-11-21 US claimed
WO-2000031149-A1 RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION LOCTITE CORPORATION (US) 2000-06-02 WO claimed
US-10100226-B2 Thermally resistant anaerobically curable compositions Henkel IP & Holding GmbH (DE) 2018-10-16 US disclosed
US-9580530-B2 Anaerobically curable compositions Henkel IP & Holding GmbH (DE) 2017-02-28 US disclosed
US-20160319162-A1 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2016-11-03 US disclosed
EP-2488580-B1 ANAEROBICALLY CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2015-09-09 EP disclosed
US-8835533-B2 Thermally resistant anaerobically curable compositions Henkel US IP LLC (US) 2014-09-16 US disclosed
EP-2207850-B1 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS HENKEL CORP (US) 2013-06-05 EP disclosed
US-20120231286-A1 ANAEROBICALLY CURABLE COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-09-13 US disclosed
EP-2488580-A2 ANAEROBICALLY CURABLE COMPOSITIONS Henkel Corporation (US) 2012-08-22 EP disclosed
WO-2011047123-A2 ANAEROBICALLY CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2011-04-21 WO disclosed
EP-2207850-A2 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS Henkel Corporation (US) 2010-07-21 EP disclosed
US-20100086796-A1 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2010-04-08 US disclosed
WO-2009058250-A2 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-05-07 WO disclosed
US-20090022894-A1 Thermally Resistant Anaerobically Curable Compositions HENKEL CORPORATION (US) 2009-01-22 US disclosed
WO-2009011819-A2 THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-01-22 WO disclosed
US-6150479-A CURABLE ADHESIVES FOR HEAT RESISTANCE LOCTITE CORPORATION (US) 2000-11-21 US disclosed
WO-2000031149-A1 RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION LOCTITE CORPORATION (US) 2000-06-02 WO disclosed